A research-module internship using electrophysiology, molecular biology, imaging, and biochemical methods to study two-pore ion channels in disease. The Wahl-Schott group combines basic research with translational approaches to identify mechanisms underlying the physiological function and pathophysiological dysfunction of ion channels clinically relevant to human diseases (including cardiac arrhythmias), using techniques such as patch-clamp, molecular and cell biological methods, and knockout mouse models, with the aim of exploring these channels as targets for disease treatment.